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CXCL12-PLGA/Pluronic Nanoparticle Internalization Abrogates CXCR4-Mediated Cell Migration

Chemokine-induced chemotaxis mediates physiological and pathological immune cell trafficking, as well as several processes involving cell migration. Among them, the role of CXCL12/CXCR4 signaling in cancer and metastasis is well known, and CXCR4 has been often targeted with small molecule-antagonist...

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Principais autores: Anissa Pisani, Roberto Donno, Arianna Gennari, Giulia Cibecchini, Federico Catalano, Roberto Marotta, Pier Paolo Pompa, Nicola Tirelli, Giuseppe Bardi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-11-01
coleção:Nanomaterials
Assuntos:
nanoparticles
chemokines
chemokine-receptor
cell-migration
immune cells
cancer
Acesso em linha:https://www.mdpi.com/2079-4991/10/11/2304
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