Ibrutinib Inhibits Angiogenesis and Tumorigenesis in a BTK-Independent Manner

BTK inhibitor (BTKi) Ibrutinib carries an increased bleeding risk compared to more selective BTKis Acalabrutinib and Zanubrutinib, however, its impact on vascular endothelium remains unknown. In this study, we found that Ibrutinib induced stronger cytotoxic effect on endothelial cells than Zanubruti...

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書誌詳細

主要な著者:	Jia Liu, Zhuojun Liu, Jing Zhang, Xiaofang Chen, Junge Chen, Linlin Sui, Jian Yu
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2022-09-01
シリーズ:	Pharmaceutics
主題:	Ibrutinib Acalabrutinib Zanubrutinib vascular endothelial dysfunction angiogenesis inhibitor
オンライン･アクセス:	https://www.mdpi.com/1999-4923/14/9/1876
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