Machine Learning Predicts Accurately Mycobacterium tuberculosis Drug Resistance From Whole Genome Sequencing Data

Background: Tuberculosis disease, caused by Mycobacterium tuberculosis, is a major public health problem. The emergence of M. tuberculosis strains resistant to existing treatments threatens to derail control efforts. Resistance is mainly conferred by mutations in genes coding for drug targets or con...

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Detalhes bibliográficos

Principais autores:	Wouter Deelder, Sofia Christakoudi, Jody Phelan, Ernest Diez Benavente, Susana Campino, Ruth McNerney, Luigi Palla, Taane G. Clark
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2019-09-01
coleção:	Frontiers in Genetics
Assuntos:	Mycobacterium tuberculosis MDR-TB XDR-TB drug resistance machine learning
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fgene.2019.00922/full
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