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Upregulation of IL-32γ in endothelial cells promotes macrophage recruitment and inflammatory progression in atherosclerosis

Abstract Atherosclerosis is characterized by chronic vascular inflammation involving endothelial dysfunction and macrophage-mediated inflammatory responses. However, the molecular mechanisms linking these processes remain incompletely understood. This study investigates the role of interleukin-32γ (...

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Principais autores: Zicong Yang, Mengzhen Liu, Yin Shi, Zhengde Lu, Zhao Lu, Yingzhong Lin, Qingwei Ji, Ling Liu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2026-02-01
Serier:Scientific Reports
Fag:
Atherosclerosis
IL-32γ
Oxidized LDL
Endothelial dysfunction
Macrophage polarization
Online adgang:https://doi.org/10.1038/s41598-026-40151-z
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