mTOR-related synaptic pathology causes autism spectrum disorder-associated functional hyperconnectivity

Autism spectrum disorder (ASD) is characterised by synaptic surplus and atypical functional connectivity. Here, the authors show that synaptic pathology in Tsc2 haploinsufficient mice is associated with autism-like behavior and cortico-striatal hyperconnectivity, and that analogous functional hyperc...

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Bibliografski detalji

Glavni autori:	Marco Pagani, Noemi Barsotti, Alice Bertero, Stavros Trakoshis, Laura Ulysse, Andrea Locarno, Ieva Miseviciute, Alessia De Felice, Carola Canella, Kaustubh Supekar, Alberto Galbusera, Vinod Menon, Raffaella Tonini, Gustavo Deco, Michael V. Lombardo, Massimo Pasqualetti, Alessandro Gozzi
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Portfolio 2021-10-01
Serija:	Nature Communications
Online pristup:	https://doi.org/10.1038/s41467-021-26131-z
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