Oncogenic activation revealed by FGFR2 genetic alterations in intrahepatic cholangiocarcinomas

Abstract Background Except for gene fusions, FGFR2 genetic alterations in intrahepatic cholangiocarcinomas (ICCs) have received limited attention, leaving patients harboring activating FGFR2 gene mutations with inadequate access to targeted therapies. Experimental design We sought to survey FGFR2 ge...

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Detalhes bibliográficos

Principais autores:	Xiaohong Pu, Liang Qi, Jia Wu Yan, Zihe Ai, Ping Wu, Fei Yang, Yao Fu, Xing Li, Min Zhang, Beicheng Sun, Shen Yue, Jun Chen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-11-01
coleção:	Cell & Bioscience
Assuntos:	Intrahepatic cholangiocarcinoma FGFR2 Translocation In-frame deletion
Acesso em linha:	https://doi.org/10.1186/s13578-023-01156-7
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