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Gypenosides regulate farnesoid X receptor-mediated bile acid and lipid metabolism in a mouse model of non-alcoholic steatohepatitis

Abstract Background Gypenosides (Gyp) are the main ingredient of the Chinese medicine, Gynostemma pentaphyllum. They are widely used in Asia as a hepatoprotective agent. Here, we elucidated the mechanism of Gyp in non-alcoholic steatohepatitis (NASH) with a focus on farnesoid X receptor (FXR)-mediat...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Hongshan Li, Yingfei Xi, Xin Xin, Huajie Tian, Yiyang Hu
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: BMC 2020-05-01
Sraith:Nutrition & Metabolism
Ábhair:
Rochtain ar líne:http://link.springer.com/article/10.1186/s12986-020-00454-y
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