Mechanism of pH-dependent activation of the sodium-proton antiporter NhaA
The pH dependence of the activity of Escherichia colimain sodium-proton antiporter NhaA is still not fully understood. Here, the authors use continuous constant pH molecular dynamics simulations to identify NhaA proton carrier residues and elucidate its gating and ion transport processes.
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Portfolio
2016-10-01
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| Serie: | Nature Communications |
| Accesso online: | https://doi.org/10.1038/ncomms12940 |
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