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Discovering the Potentials of Four Phage Endolysins to Combat Gram-Negative Infections

Endolysin-based therapeutics are promising antibacterial agents and can successfully supplement the existing antibacterial drugs array. It is specifically important in the case of Gram-negative pathogens, e.g., ESKAPE group bacteria, which includes Enterococcus faecium, Staphylococcus aureus, Klebsi...

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Principais autores: Daria V. Vasina, Nataliia P. Antonova, Igor V. Grigoriev, Victoria S. Yakimakha, Anastasiya M. Lendel, Maria A. Nikiforova, Andrei A. Pochtovyi, Timofey A. Remizov, Evgeny V. Usachev, Natalia V. Shevlyagina, Vladimir G. Zhukhovitsky, Mikhail V. Fursov, Vasiliy D. Potapov, Aleksei M. Vorobev, Andrey V. Aleshkin, Aleksei I. Laishevtsev, Valentine V. Makarov, Sergey M. Yudin, Artem P. Tkachuk, Vladimir A. Gushchin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-10-01
coleção:Frontiers in Microbiology
Assuntos:
endolysin
Gram-negative bacteria
antimicrobial agents
local infection
animal models
safety
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fmicb.2021.748718/full
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