Distribution Study of 5-[5-(trifluoromethyl)-1,2-oxazole-3-yl]-furan-2-sulfonamide and Its Metabolites in Rats

INTRODUCTION. This article continues a series of publications on the pharmacokinetics of 5-[5-(trifluoromethyl)-1,2-oxazole-3-yl]-furan-2-sulfonamide (TFISA), a novel compound for the treatment of open-angle glaucoma. The distribution of TFISA and its metabolites in rat organs and tissues has not be...

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Principais autores:	I. I. Yaichkov, A. L. Khokhlov, M. K. Korsakov, N. N. Volkhin, S. S. Petukhov, O. E. Lazariants, A. V. Korovina
Format:	Artigo
Jezik:	Russo
Izdano:	Federal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’) 2025-07-01
Serija:	Регуляторные исследования и экспертиза лекарственных средств
Teme:	ингибитор карбоангидразы ii, n-гидроксисульфонамид глазные капли крысы вэжх-мс/мс валидация распределение фармакокинетика глаукома доклинические исследования
Online dostop:	https://www.vedomostincesmp.ru/jour/article/view/743
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