Brosimine B and the biphasic dose-response: insights into hormesis and retinal neuroprotection

IntroductionThe biphasic dose-response behavior, also known as hormesis, is a characteristic feature of numerous natural products. It is defined by beneficial effects at low concentrations and toxicity at higher doses. This study investigates the hormetic effects of Brosimine B, a flavonoid derived...

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主要な著者:	Susanne Suely Santos Fonseca, Natacha M. S. Port’s, Gisele Priscila Soares Aguiar, Eliã P. Botelho, Nádia M. G. Couto, Wandson Braamcamp Souza Pinheiro, André Salim Khayat, Elizabeth S. Yamada, Edmar T. Costa, Chubert Bernardo C. Sena, Mara Silvia P. Arruda, Carlomagno P. Bahia, Antonio Pereira
フォーマット:	Artigo
言語:	Inglês
出版事項:	Frontiers Media S.A. 2025-04-01
シリーズ:	Frontiers in Pharmacology
主題:	oxidative stress Brosimine b retinal cell neuroprotection hormesis natural products
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1558726/full
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