Identification of compounds that rescue otic and myelination defects in the zebrafish adgrg6 (gpr126) mutant
Adgrg6 (Gpr126) is an adhesion class G protein-coupled receptor with a conserved role in myelination of the peripheral nervous system. In the zebrafish, mutation of adgrg6 also results in defects in the inner ear: otic tissue fails to down-regulate versican gene expression and morphogenesis is disru...
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| Huvudupphov: | , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
eLife Sciences Publications Ltd
2019-06-01
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| Serie: | eLife |
| Ämnen: | |
| Länkar: | https://elifesciences.org/articles/44889 |
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