DC-SIGN increases the affinity of HIV-1 envelope glycoprotein interaction with CD4.
Mannose-binding C-type lectin receptors, expressed on Langerhans cells and subepithelial dendritic cells (DCs) of cervico-vaginal tissues, play an important role in HIV-1 capture and subsequent dissemination to lymph nodes. DC-SIGN has been implicated in both productive infection of DCs and the DC-m...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Public Library of Science (PLoS)
2011-01-01
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| Σειρά: | PLoS ONE |
| Διαθέσιμο Online: | https://doi.org/10.1371/journal.pone.0028307 |
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