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An Efficient and Practical Chemoenzymatic Route to (3R,3aR,6R,6aR)-Hexahydrofuro[3,2-b]furan-6-amino-3-ol (6-Aminoisomannide) from Renewable Sources

The synthesis of 6-aminoisomannide is easily achieved starting from the renewable, inexpensive, and commercially available isosorbide in 66% overall yield. A biocatalyzed highly regioselective acetylation of the 3-endo hydroxyl group of isosorbide was followed by the stereospecific interconversion o...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Valerio Zullo, Antonella Petri, Anna Iuliano
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Georg Thieme Verlag KG 2021-07-01
Rangatū:SynOpen
Ngā marau:
Urunga tuihono:http://www.thieme-connect.de/DOI/DOI?10.1055/a-1532-5825
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