Inhibition of ALOX12–12-HETE Alleviates Lung Ischemia–Reperfusion Injury by Reducing Endothelial Ferroptosis-Mediated Neutrophil Extracellular Trap Formation

Lung ischemia–reperfusion injury (IRI) stands as the primary culprit behind primary graft dysfunction (PGD) after lung transplantation, yet viable therapeutic options are lacking. In the present study, we used a murine hilar clamp (1 h) and reperfusion (3 h) model to study IRI. The left lung tissues...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Chongwu Li, Peigen Gao, Fenghui Zhuang, Tao Wang, Zeyu Wang, Guodong Wu, Ziheng Zhou, Huikang Xie, Dong Xie, Deping Zhao, Junqi Wu, Chang Chen
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Association for the Advancement of Science (AAAS) 2024-01-01
Serie:	Research
Accesso online:	https://spj.science.org/doi/10.34133/research.0473
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!