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Phagosomal TLR signaling upon Borrelia burgdorferi infection

Internalization of live Borrelia burgdorferi followed by their degradation within phagosomal compartments, allows for the release not only of lipoproteins but of other microbial products, such as nucleic acids, needed to elicit a full and broad inflammatory response in monocytes/macrophages. Toll-l...

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Principais autores: Jorge Luis Cervantes, Kelly Lynn Hawley, Sarah Jane Benjamin, Bennett eWeinerman, Stephanie eLuu, Juan Carlos Salazar
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2014-05-01
Serier:Frontiers in Cellular and Infection Microbiology
Fag:
Borrelia burgdorferi
Lyme Disease
Toll-Like Receptors
innate immunity
phagosomal signaling
Online adgang:http://journal.frontiersin.org/Journal/10.3389/fcimb.2014.00055/full
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