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The Insertion of an Evolutionary Lost Four-Amino-Acid Cytoplasmic Tail Peptide into a Syncytin-1 Vaccine Increases T- and B-Cell Responses in Mice

Human endogenous retrovirus type W (HERV-W) is expressed in various cancers. We previously developed an adenovirus-vectored cancer vaccine targeting HERV-W by encoding an assembled HERV-W group-specific antigen sequence and the HERV-W envelope sequence Syncytin-1. Syncytin-1 is constitutively fusoge...

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Príomhchruthaitheoirí: Isabella Skandorff, Jasmin Gille, Emeline Ragonnaud, Anne-Marie Andersson, Silke Schrödel, Christian Thirion, Ralf Wagner, Peter Johannes Holst
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: MDPI AG 2023-08-01
Sraith:Viruses
Ábhair:
Rochtain ar líne:https://www.mdpi.com/1999-4915/15/8/1686
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