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Clinical trials with interim analyses: standardizing terminology to increase clarity

Abstract Interim analyses for group-sequential decision-making are prevalent in clinical trials. Methodology is well established and has been routinely implemented over the last decades. Still, confusions and uncertainties on aspects of how to operationalize and interpret interim analyses exist for...

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Principais autores: Elina Asikanius, Benjamin Hofner, Lisa V. Hampson, Gernot Wassmer, Christopher Jennison, Tobias Mielke, Cornelia Ursula Kunz, Kaspar Rufibach
格式: Artigo
语言:Inglês
出版: BMC 2025-07-01
丛编:Trials
在线阅读:https://doi.org/10.1186/s13063-025-08942-3
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