Evaluation of Staphylococcal Bacteriophage Sb-1 as an Adjunctive Agent to Antibiotics Against Rifampin-Resistant Staphylococcus aureus Biofilms

Rifampin plays a crucial role in the treatment of staphylococcal implant-associated infection, as it is the only antibiotic capable of eradicating Staphylococcus aureus biofilms. However, the emergence of rifampin resistance strongly limits its use. Combinatorial therapy of antibiotics and bacteriop...

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Hauptverfasser:	Lei Wang, Tamta Tkhilaishvili, Andrej Trampuz, Mercedes Gonzalez Moreno
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2020-11-01
Schriftenreihe:	Frontiers in Microbiology
Schlagworte:	rifampin-resistant Staphylococcus aureus bacterial biofilm antibiotic–bacteriophage combination phage therapy synergism isothermal microcalorimetry
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fmicb.2020.602057/full
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