Radiotherapy-synergized in situ hydrogel vaccine with engineered Lactococcus lactis FOLactis potentiates anti-tumor immunity in pancreatic cancer

BackgroundImmunotherapy has emerged as a promising strategy for pancreatic cancer. Radiotherapy not only mediates direct tumor cell killing but also provides a source of tumor antigens for dendritic cells (DCs) uptake and presentation via the induction of immunogenic cell death (ICD). However, the l...

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Autori principali:	Jingjing Chen, Qiaoli Wang, Junmeng Zhu, Xinyuan Bai, Haochen Tang, Xiang Kong, Lu Zou, Qinghua Zheng, Yingxin Wang, Yan Zhao, Baorui Liu, Fanyan Meng, Juan Du
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2026-06-01
Serie:	Frontiers in Immunology
Soggetti:	hydrogel in situ tumor vaccine Lactococcus lactis pancreatic cancer radiotherapy
Accesso online:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1789212/full
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