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Viral vector-mediated downregulation of RhoA increases survival and axonal regeneration of retinal ganglion cells

The Rho/ROCK pathway is a promising therapeutic target in neurodegenerative and neurotraumatic diseases. Pharmacological inhibition of various pathway members has been shown to promote neuronal regeneration and survival. However, because pharmacological inhibitors are inherently limited in their spe...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Jan Christoph Koch, Lars eTönges, Uwe eMichel, Mathias eBähr, Paul eLingor
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2014-09-01
Rangatū:Frontiers in Cellular Neuroscience
Ngā marau:
Urunga tuihono:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00273/full
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