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ER stress-induced YAP upregulation leads to chondrocyte phenotype loss in age-related osteoarthritis

BackgroundOsteoarthritis (OA) is a common degenerative joint disease, leading to pain and restricted mobility. Age-related endoplasmic reticulum (ER) stress has been implicated in the pathogenesis of OA, but the underlying mechanisms remain unclear. This study aims to explore the relationship betwee...

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Hlavní autoři: Yanchun Gao, Haifeng Wei, Xiaoyuan Peng, Chenchen Wang, Hongyi Zhu, Junhui Yin
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2024-11-01
Edice:Frontiers in Pharmacology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fphar.2024.1476255/full
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