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Yes-associated protein (YAP) and transcriptional coactivator with a PDZ-binding motif (TAZ): a nexus between hypoxia and cancer

Hypoxia is a common feature of solid tumors. As transcription factors, hypoxia-inducible factors (HIFs) are the master regulators of the hypoxic microenvironment; their target genes function in tumorigenesis and tumor development. Intriguingly, both yes-associated protein (YAP) and its paralog trans...

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Principais autores: Chenxi Zhao, Chenming Zeng, Song Ye, Xiaoyang Dai, Qiaojun He, Bo Yang, Hong Zhu
格式: Artigo
語言:Inglês
出版: Elsevier 2020-06-01
叢編:Acta Pharmaceutica Sinica B
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在線閱讀:http://www.sciencedirect.com/science/article/pii/S2211383519308214
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