Synthesis of Symmetrical Monocarbonyl Analogs of Curcumin Containing a 2-Bromobenzylidene Moiety and Spectrophotometric Assessment of Their Reactivity with 2-(Dimethylamino)ethanthiol

The cross-conjugated dienones containing the 1,5-diaryl-3-oxo-1,4-pentadienyl pharmacophore have diverse biological activities. These sometimes-called monocarbonyl analogs of curcumin (MACs) have especially pronounced biological activity when containing an electron-withdrawing group at the ortho-pos...

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Hauptverfasser:	Zlatko Lozanovski, Ivana Todorovska, Katerina Dragarska, Jane Bogdanov
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2023-11-01
Schriftenreihe:	Chemistry Proceedings
Schlagworte:	monocarbonyl analogs of curcumin symmetrical 2-bromobenzylidene MACs synthesis 2-(dimethylamino)ethanethiol Michael reaction with thiols UV-Vis spectroscopy
Online-Zugang:	https://www.mdpi.com/2673-4583/14/1/7
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