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What is the relevance of Ikaros gene deletions as a prognostic marker in pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia?

New prognostic markers are needed for upfront identification of patients with acute lymphocytic leukemia with a high risk of relapse or who are not likely to respond to the most aggressive chemotherapy. We focused our analysis on Ikaros (IKZF1) gene deletions in a homogeneous cohort of 410 pediatric...

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Detalles Bibliográficos
Principais autores: Chiara Palmi, Maria Grazia Valsecchi, Giulia Longinotti, Daniela Silvestri, Valentina Carrino, Valentino Conter, Giuseppe Basso, Andrea Biondi, Geertruy Te Kronnie, Giovanni Cazzaniga
Formato: Artigo
Idioma:Inglês
Publicado: Ferrata Storti Foundation 2013-08-01
Series:Haematologica
Acceso en liña:https://haematologica.org/article/view/6747
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