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Intestinal gluconeogenesis controls the neonatal development of hypothalamic feeding circuits

Objective: Intestinal gluconeogenesis (IGN) regulates adult energy homeostasis in part by controlling the same hypothalamic targets as leptin. In neonates, leptin exhibits a neonatal surge controlling axonal outgrowth between the different hypothalamic nuclei involved in feeding circuits and autonom...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Judith Estrada-Meza, Jasmine Videlo, Clara Bron, Adeline Duchampt, Cécile Saint-Béat, Mickael Zergane, Marine Silva, Fabienne Rajas, Sebastien G. Bouret, Gilles Mithieux, Amandine Gautier-Stein
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2024-11-01
Schriftenreihe:Molecular Metabolism
Schlagworte:
Intestinal gluconeogenesis
Neonatal period
Obesity
Hypothalamic development
Agouti-related peptide (AgRP)
Pro-opiomelanocortin (POMC)
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2212877824001674
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