Loss of Mir146b with aging contributes to inflammation and mitochondrial dysfunction in thioglycollate-elicited peritoneal macrophages

Macrophages undergo programmatic changes with age, leading to altered cytokine polarization and immune dysfunction, shifting these critical immune cells from protective sentinels to disease promoters. The molecular mechanisms underlying macrophage inflammaging are poorly understood. Using an unbiase...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Andrea Santeford, Aaron Y Lee, Abdoulaye Sene, Lynn M Hassman, Alexey A Sergushichev, Ekaterina Loginicheva, Maxim N Artyomov, Philip A Ruzycki, Rajendra S Apte
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	eLife Sciences Publications Ltd 2021-08-01
Σειρά:	eLife
Θέματα:	macrophage aging mitochondrial metabolism
Διαθέσιμο Online:	https://elifesciences.org/articles/66703
Ετικέτες:	Προσθήκη ετικέτας Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!