Identification of a Novel CD8 T Cell Epitope Derived from Plasmodium berghei Protective Liver-Stage Antigen

We recently identified novel Plasmodium berghei (Pb) liver stage (LS) genes that as DNA vaccines significantly reduce Pb LS parasite burden (LPB) in C57Bl/6 (B6) mice through a mechanism mediated, in part, by CD8 T cells. In this study, we sought to determine fine antigen (Ag) specificities of CD8 T...

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Principais autores:	Alexander Pichugin, Stasya Zarling, Leah Perazzo, Patrick Emmet Duffy, Hidde Lolke Ploegh, Urszula Krzych
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2018-01-01
coleção:	Frontiers in Immunology
Assuntos:	CD8 T cells epitope prediction Plasmodium caged MHC-tetramers minigene
Acesso em linha:	http://journal.frontiersin.org/article/10.3389/fimmu.2018.00091/full
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