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Cathepsin K regulates the tumor growth and metastasis by IL-17/CTSK/EMT axis and mediates M2 macrophage polarization in castration-resistant prostate cancer

Abstract A common stage of advanced prostate cancer is castration-resistant prostate cancer (CRPC), greater understanding of which is required in order to address and solve the clinically difficult challenge. Cathepsin K (CTSK) is a cysteine protease that usually has a strong activity of degrading e...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Ning Wu, YouZhi Wang, KeKe Wang, BoQiang Zhong, YiHao Liao, JiaMing Liang, Ning Jiang
التنسيق: Artigo
اللغة:Inglês
منشور في: Nature Publishing Group 2022-09-01
سلاسل:Cell Death and Disease
الوصول للمادة أونلاين:https://doi.org/10.1038/s41419-022-05215-8
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