A diagnostic stewardship bundle approach to facilitate same-day optimal antimicrobial therapy in gram-negative sepsis: a quasi-experimental study

Abstract It is challenging to reduce time to optimal antimicrobial therapy in patients with sepsis for microbiology laboratories in low to middle-income countries. We evaluated the diagnostic accuracy and impact of a diagnostic stewardship bundle titled “Sepsis-24” to reduce turnaround time (TAT) of...

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Autori principali:	Ayush Gupta, Saurabh Saigal, Sagar Khadanga, Shashank Purwar, Abhishek Goyal, Alkesh Khurana, Pandita Kawal Krishan
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2026-04-01
Serie:	Scientific Reports
Soggetti:	Gram-negative Sepsis diagnostic stewardship EUCAST RAST direct microbial identification LMIC blood culture
Accesso online:	https://doi.org/10.1038/s41598-026-46677-6
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