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Bridging the gap: addressing real-life challenges to the implementation of DTG/3TC in treatment-naive people living with HIV

Dolutegravir/lamivudine (DTG/3TC), used as a two-drug regimen (2DR), has demonstrated non-inferiority to traditional three-drug regimens (3DRs) in treatment-naive people with HIV (PWH), with sustained virological efficacy, favorable tolerability, and a good safety profile. However, its implementatio...

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Principais autores: Andrea Giacomelli, Gianmaria Baldin, Valeria Bono, Arturo Ciccullo, Maria Mazzitelli, Mariacristina Poliseno, Marco Ridolfi, Federica Sozio, Elisabetta Teti, Giulia Marchetti
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-01-01
Serier:Frontiers in Virology
Fag:
antiretroviral therapy simplification
dolutegravir/lamivudine
treatment-naive people with HIV
two-drug regimen (2DR)
viro-immunological outcomes
Online adgang:https://www.frontiersin.org/articles/10.3389/fviro.2025.1749039/full
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