The chromatin landscape of pathogenic transcriptional cell states in rheumatoid arthritis

Abstract Synovial tissue inflammation is a hallmark of rheumatoid arthritis (RA). Recent work has identified prominent pathogenic cell states in inflamed RA synovial tissue, such as T peripheral helper cells; however, the epigenetic regulation of these states has yet to be defined. Here, we examine...

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Detalles Bibliográficos

Principais autores:	Kathryn Weinand, Saori Sakaue, Aparna Nathan, Anna Helena Jonsson, Fan Zhang, Gerald F. M. Watts, Majd Al Suqri, Zhu Zhu, Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network, Deepak A. Rao, Jennifer H. Anolik, Michael B. Brenner, Laura T. Donlin, Kevin Wei, Soumya Raychaudhuri
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Portfolio 2024-05-01
Series:	Nature Communications
Acceso en liña:	https://doi.org/10.1038/s41467-024-48620-7
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