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Regulation of the MDM2‐p53 pathway by the ubiquitin ligase HERC2

The p53 tumor suppressor protein is a transcription factor that plays a prominent role in protecting cells from malignant transformation. Protein levels of p53 and its transcriptional activity are tightly regulated by the ubiquitin E3 ligase MDM2, the gene expression of which is transcriptionally re...

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Bibliografische gegevens
Hoofdauteurs: Jesús García‐Cano, Susana Sánchez‐Tena, Joan Sala‐Gaston, Agnès Figueras, Francesc Viñals, Ramon Bartrons, Francesc Ventura, Jose Luis Rosa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Wiley 2020-01-01
Reeks:Molecular Oncology
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Online toegang:https://doi.org/10.1002/1878-0261.12592
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