Medroxyprogesterone promotes neuronal survival after cerebral ischemic stroke by inhibiting PARthanatos

IntroductionCerebral ischemic stroke (CIS) is caused by the interruption of cerebral blood circulation due to thrombosis or embolism and is the second-leading cause of mortality worldwide. The neuronal death and motor dysfunction resulting from CIS are primarily attributed to the induction of PARtha...

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Autori principali:	Chang-Ling Yue, Yan-Xia Ding, Meng Chen, Yu-Xin Shen, Ao-Meng Hu, Hai Huang, Zhao-Huan Zhang, Ying-Xin Zhou, Xiao-Hui Xu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2025-02-01
Serie:	Frontiers in Pharmacology
Soggetti:	medroxyprogesterone PARthanatos apoptosis-inducing factor extracellular signal-regulated kinase cerebral ischemic stroke approved drug library
Accesso online:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1487436/full
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