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Development and Characterization of New Miconazole-Based Microemulsions for Buccal Delivery by Implementing a Full Factorial Design Modeling

This research aimed to develop miconazole-based microemulsions using oleic acid as a natural lipophilic phase and a stabilizer mixture comprising Tween 20 and PEG 400 to solubilize miconazole as an antifungal agent known for its activity in oral candidiasis and to improve its bioavailability. The fo...

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Principais autores: Marina-Theodora Talianu, Cristina-Elena Dinu-Pîrvu, Mihaela Violeta Ghica, Valentina Anuţa, Răzvan Mihai Prisada, Lăcrămioara Popa
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-02-01
Serier:Pharmaceutics
Fag:
miconazole base
solubilization
UV-spectroscopy
phase diagrams
stabilizers
microemulsions
Online adgang:https://www.mdpi.com/1999-4923/16/2/271
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