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Parvovirus B19 and Cellular Transcriptome Dynamics in Differentiating Erythroid Progenitor Cells

Parvovirus B19 (B19V) is a human ssDNA virus with ample pathogenic potential. It is characterized by a selective tropism for erythroid progenitor cells (EPC), exerting a cytotoxic effect with blockade of erythropoiesis. In our work, we investigated both viral and cellular expression profile in the c...

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Principais autores: Erika Fasano, Niccolò Guglietta, Federica Bichicchi, Ilaria Gasperini, Elisabetta Manaresi, Giorgio Gallinella
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-12-01
Serier:Viruses
Fag:
Parvovirus B19
erythroid progenitor cells
cytofluorimetry
FISH
high-throughput sequencing
bioinformatics
Online adgang:https://www.mdpi.com/1999-4915/18/1/39
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