Piezo1 Regulation Involves Lipid Domains and the Cytoskeleton and Is Favored by the Stomatocyte–Discocyte–Echinocyte Transformation

Piezo1 is a mechanosensitive ion channel required for various biological processes, but its regulation remains poorly understood. Here, we used erythrocytes to address this question since they display Piezo1 clusters, a strong and dynamic cytoskeleton and three types of submicrometric lipid domains,...

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Detalles Bibliográficos

Principais autores:	Amaury Stommen, Marine Ghodsi, Anne-Sophie Cloos, Louise Conrard, Andra C. Dumitru, Patrick Henriet, Christophe E. Pierreux, David Alsteens, Donatienne Tyteca
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2023-12-01
Series:	Biomolecules
Assuntos:	Piezo1 distribution Piezo1 chemical activation Yoda1 membrane stiffness erythrocyte morphology cholesterol
Acceso en liña:	https://www.mdpi.com/2218-273X/14/1/51
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