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Chronic Astrocytic TNFα Production in the Preoptic-Basal Forebrain Causes Aging-like Sleep–Wake Disturbances in Young Mice

Sleep disruption is a frequent problem of advancing age, often accompanied by low-grade chronic central and peripheral inflammation. We examined whether chronic neuroinflammation in the preoptic and basal forebrain area (POA-BF), a critical sleep–wake regulatory structure, contributes to this disrup...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Andrey Kostin, Md. Aftab Alam, Anton Saevskiy, Md. Noor Alam
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2024-05-01
Schriftenreihe:Cells
Schlagworte:
preoptic area
basal forebrain
inflammation
sleep–wake disturbances
TNFα
astrocytes
Online-Zugang:https://www.mdpi.com/2073-4409/13/11/894
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