A hormetic transcriptional program coregulates invasion, proliferation and dormancy to define metastatic potential
Abstract Metastasis remains the leading cause of cancer mortality, yet the factors that determine metastatic competence and the timing of its acquisition are not well understood. Using human breast cancer cohorts and multi-omics in preclinical models, here we show that cells exit the primary tumor w...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Portfolio
2026-03-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-026-70242-4 |
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