Divergent roles for complement components C3 and C4 in controlling Klebsiella pneumoniae gut colonization and systemic dissemination

ABSTRACT Klebsiella pneumoniae is an escalating public health threat driven by the emergence of antibiotic-resistant and hyper-encapsulated strains that spread systemically from the gut. The immune defenses preventing gut colonization and dissemination remain poorly defined. Here, we identify distin...

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Auteurs principaux:	Juan D. Valencia-Bacca, Jamie E. Jennings-Gee, Noah A. Nutter, Alexis E. Adams-Sims, Abigail A. Hegarty, Hope L. Nzuki, Ravinder K. Nagpal, M. Ammar Zafar, Karen M. Haas
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology 2026-03-01
Collection:	mBio
Sujets:	Klebsiella pneumoniae complement deficiency intestinal colonization antibiotic resistance
Accès en ligne:	https://journals.asm.org/doi/10.1128/mbio.03416-25
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