Molecular design of orthogonal stacking system at the complex interface of HtrA PDZ domain with its peptide ligands

The high temperature requirement A (HtrA) protease plays a crucial role in protein quality control and cell fate. The enzyme contains a catalytic protease domain and a regulatory PDZ domain; the latter determines the substrate specificity of the former by specifically binding to the C-terminal hydro...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Zhang Dingwa, He Deyong, Pan Xiaoliang, Xu Yaping, Liu Lijun
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Serbian Chemical Society 2019-01-01
coleção:	Journal of the Serbian Chemical Society
Assuntos:	htra protease htra pdz domain peptide ligand orthogonal π-cation-π stacking synergistic effect
Acesso em linha:	http://www.doiserbia.nb.rs/img/doi/0352-5139/2019/0352-51391900029Z.pdf
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!