PINK1 functions in mitophagy and mitochondrial homeostasis during mice oocyte maturation

Abstract Background As a serine/threonine kinase, PINK1 (PTEN-induced putative kinase 1) is widely expressed in mammalian tissues and cells, especially in the female reproductive system. However, its role in meiotic oocytes remains obscure. Here, we report that murine oocytes overexpressing Pink1 ar...

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Detalles Bibliográficos

Autores principales:	Shiwei Wang, Xuan Wu, Mengmeng Zhang, Yixiao Zhu, Yajun Guo, Shuang Song, Shenming Zeng
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2025-09-01
Colección:	Cell & Bioscience
Materias:	PINK1 RAB8A Mitophagy Mitochondrial homeostasis Oocyte
Acceso en línea:	https://doi.org/10.1186/s13578-025-01460-4
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