Wnt activation disturbs cell competition and causes diffuse invasion of transformed cells through NF-κB-MMP21 pathway

Abstract Normal epithelial cells exert their competitive advantage over RasV12-transformed cells and eliminate them into the apical lumen via cell competition. However, the internal or external factors that compromise cell competition and provoke carcinogenesis remain elusive. In this study, we exam...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Kazuki Nakai, Hancheng Lin, Shotaro Yamano, Shinya Tanaka, Sho Kitamoto, Hitoshi Saitoh, Kenta Sakuma, Junpei Kurauchi, Eilma Akter, Masamitsu Konno, Kojiro Ishibashi, Ryo Kamata, Akihiro Ohashi, Jun Koseki, Hirotaka Takahashi, Hideshi Yokoyama, Yukihiro Shiraki, Atsushi Enomoto, Sohei Abe, Yoku Hayakawa, Tetsuo Ushiku, Michihiro Mutoh, Yasuyuki Fujita, Shunsuke Kon
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2023-11-01
coleção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-023-42774-6
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!