Chromosomal breakage and sister chromatid exchange analysis in breast cancer patients with heterozygous BLM gene variants

BLM, a member of the RecQ helicase family, plays an important role in DNA repair, and its biallelic mutations cause autosomal recessive Bloom syndrome, a disease characterized by elevated levels of sister chromatid exchange (SCE) in affected individuals and hereditary cancer susceptibility in carrie...

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Autores principales:	Yararbas Kanay, Sayar Ceyhan, Tavukcu Cemre, Korkmaz Taner, Çankaya Dilara Çakmak, Mutlu Elif Karabacak, Özbek Uğur
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	De Gruyter 2024-08-01
Colección:	Türk Biyokimya Dergisi
Materias:	blm chromosomal instability sister chromatid exchange sce dna repair mechanisms chromosome breakage
Acceso en línea:	https://doi.org/10.1515/tjb-2024-0070
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