Antibiotics and phages drive region-specific diversity of OmpK36 in Klebsiella pneumoniae

ABSTRACT The Enterobacterales outer membrane is impermeable to many antibiotics, but they can enter the cell via channel proteins, called porins. In Klebsiella pneumoniae, the porin OmpK36 is a major determinant of antibiotic resistance. Insertion of amino acids into the L3 constriction loop is freq...

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Hlavní autoři:	Guilhem Royer, Raphaël Laurenceau, Nicolas Cabanel, Benjamin Bardiaux, Karol Melissa Cerdas-Mejías, David Bikard, Isabelle Rosinski-Chupin, Philippe Glaser
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2025-09-01
Edice:	mBio
Témata:	porins genome analysis bacteriophages antibiotic resistance OmpK36
On-line přístup:	https://journals.asm.org/doi/10.1128/mbio.01343-25
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