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Skin‐draining lymph node priming is sufficient to induce sterile immunity against pre‐erythrocytic malaria

Abstract The Plasmodium‐infected hepatocyte has been considered necessary to prime the immune responses leading to sterile protection after vaccination with attenuated sporozoites. However, it has recently been demonstrated that priming also occurs in the skin. We wished to establish if sterile prot...

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Principais autores: Michel Obeid, Jean‐François Franetich, Audrey Lorthiois, Audrey Gego, Anne Charlotte Grüner, Maurel Tefit, Claude Boucheix, Georges Snounou, Dominique Mazier
格式: Artigo
语言:Inglês
出版: Springer Nature 2012-12-01
丛编:EMBO Molecular Medicine
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在线阅读:https://doi.org/10.1002/emmm.201201677
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