Comparison of a Rat Primary Cell-Based Blood-Brain Barrier Model With Epithelial and Brain Endothelial Cell Lines: Gene Expression and Drug Transport

Cell culture-based blood-brain barrier (BBB) models are useful tools for screening of CNS drug candidates. Cell sources for BBB models include primary brain endothelial cells or immortalized brain endothelial cell lines. Despite their well-known differences, epithelial cell lines are also used as su...

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Hlavní autoři:	Szilvia Veszelka, András Tóth, Fruzsina R. Walter, Andrea E. Tóth, Ilona Gróf, Mária Mészáros, Alexandra Bocsik, Éva Hellinger, Monika Vastag, Gábor Rákhely, Mária A. Deli
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2018-05-01
Edice:	Frontiers in Molecular Neuroscience
Témata:	blood-brain barrier brain endothelial cells Caco-2 MDCK RBE4 hCMEC/D3
On-line přístup:	https://www.frontiersin.org/article/10.3389/fnmol.2018.00166/full
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