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Preparation of Sesquiterpene Lactone-Loaded PLA Nanoparticles and Evaluation of Their Antitrypanosomal Activity

Human African trypanosomiasis (HAT), also commonly known as sleeping sickness, is a neglected tropical disease affecting millions of people in poorly developed regions in sub-Saharan Africa. There is no satisfactory treatment for this infection. The investment necessary to bring new drugs to the mar...

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Main Authors: Njogu M. Kimani, Solveig Backhaus, Josphat C. Matasyoh, Marcel Kaiser, Fabian C. Herrmann, Thomas J. Schmidt, Klaus Langer
Format: Artigo
Language:Inglês
Published: MDPI AG 2019-06-01
Series:Molecules
Subjects:
human African trypanosomiasis
sesquiterpene lactones
nanoparticles
PLA
<i>Trypanosoma brucei</i>
Online Access:https://www.mdpi.com/1420-3049/24/11/2110
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