Ubiquitination and degradation of NF90 by Tim-3 inhibits antiviral innate immunity
Nuclear factor 90 (NF90) is a novel virus sensor that serves to initiate antiviral innate immunity by triggering stress granule (SG) formation. However, the regulation of the NF90-SG pathway remains largely unclear. We found that Tim-3, an immune checkpoint inhibitor, promotes the ubiquitination and...
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| Autori principali: | , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications Ltd
2021-06-01
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| Serie: | eLife |
| Soggetti: | |
| Accesso online: | https://elifesciences.org/articles/66501 |
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