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Resveratrol as a Dual MAPK/STAT3 Inhibitor in Glioblastoma: Mutation-Dependent Therapeutic Efficacy

<b>Background</b>: Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor with limited treatment options. Tumors harboring the BRAF<sup>V600E</sup> mutation exhibit aggressive behavior and present therapeutic challenges. Although dabrafenib/trametinib (D+T) target the BRAF/MAPK pat...

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Autori principali: Aziz Ullah, Mengjie Li, Mohammad Abdullah Aljasir, Sajjad Ahmad, Chuanchun Han
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2026-05-01
Serie:Life
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Accesso online:https://www.mdpi.com/2075-1729/16/5/772
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